Professor of Chemistry ,Assistant dean

Phone: (86)27- 87559484


Academic Areas: Analytical Chemistry

Recipient of 1000 Young Talent Program (2012), which is funded by Chinese government with the goal of supporting the top excellent young scientist (under their 40’s) in the whole world who will come back to work in China. My research focuses on (1) Nano-Materials; (2) Computation Devices based on Bio-Macromolecules; (3) Hybrid Organic-Inorganic Compounds and (4) Early Detection of Cancer Cells.  Published 36 SCI indexed paper, including 1 Chem. Rev.; 6 J. Am. Chem. Soc.; 4 Adv. Mater.; 1 Proc. Natl. Acad. Sci. USA; 1 Angew. Chem. Int. Ed. as the first author or the corresponding author. The highest impact factor is 41.298, the total impact factor are more than 300. These papers have been cited by more than 1600 times, with H factor 21. 


Academic Degrees

3. PhD: Physical Chemistry, 2003.9 ~ 2008.6  Institute of Chemistry,

  Chinese Academy of Sciences, Beijing, China. 

  Supervisor: Prof. Lei Jiang (Chinese Academy of Sciences Academician)  

2. Bachelor of Engineering: Applied Chemistry, 1999.9 ~ 2003.6  

  Huazhong University of Science and Technology, Wuhan, China.  

1. Bachelor of Arts: English for Science and Technology, (TEM Band 8), 1999.9 ~ 2003.6  

  Huazhong University of Science and Technology, Wuhan, China. 

Professional Experience

4. Professor, Ph.D.Supervisor:2012.9 ~ present

  School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan, China

3. Post-doc: 2008.9 ~ 2012.8  

  UC Santa Barbara, Santa Barbara CA 93106, United States  

  Mentors: Prof. Alan J. Heeger (2000 Nobel Prize Winner in Chemistry)  
        Prof. Kevin W. Plaxco  

2. Visiting scholar: 2007.10 ~ 2008.6

  Peking University  

  Mentor: Prof. Yugang Wang  

1. Visiting scholar: 2007.5 ~ 2007.8  

  University of Science and Technology of China  

  Mentor: Prof. Guangzhao Zhang  


Selected Publications

A: 36 Papers (Impact Factor is larger than 300): 
B: As the first author and Corresponding Author: 1 Chem. Rev.; 6 J. Am. Chem. Soc.; 4 Adv. Mater.; 1 Proc. Natl. Acad. Sci. USA; 1 Angew. Chem. Int. Ed. 
C: Total Cited by more than 1900 times; 
D: H Factor is 20.  

1. Juwen Shen, Yuebin Li, Fan Xia* and Xiaolei Zuo, “Recent development of sandwich assay based on the nano-biotechnologies for proteins, nucleic acids, small molecules and ions.” Chem. Rev., 2014, in press.
Impact Factor: 41.298
2. Fan Xia*, Ruixue Duan, Xialei Zuo, et al. Quadratic isothermal amplification for the detection of microRNA, Nature Protocols, 2014, 9, 597.
Impact Factor: 7.960  
3. Nannan Liu, Yanan Jiang, Yahong Zhou, Fan Xia,* Wei Guo,*and Lei Jiang. “Two-Way Nanopore Sensing of Sequence-Specific Oligonucleotides and Small-Molecule Targets in Complex Matrices Using Integrated DNA Supersandwich Structures” Angew. Chem. Int. Ed., 2013, 52, 2007. (Inside Cover)  
Impact Factor: 13.734 
4. Ruixue Duan, Xiaolei Zuo, Shutao Wang, Xiyun Quan, Fan Xia*. “Lab in a Tube: Ultrasensitive Detection of MicroRNAs at the single-Cell level and in Breast Cancer Patients Using Quadratic Isothermal Amplification” J. Am. Chem. Soc., 2013, 135, 4604.  
Impact Factor: 10.677    
5. Yanan Jiang, Nannan Liu, Wei guo,* Fan Xia,* and Lei Jiang. “Highly-Efficient Gating of Solid-State Nanochannels by DNA Supersandwich Structure Containing ATP Aptamers: A Nanofluidic IMPLICATION Logic Device” J. Am. Chem. Soc., 2012, 134, 15395. 
Impact Factor: 10.677   
6. Duan, Ruixue, Fan Xia, and Lei Jiang. “Constructing Tunable Nanopores and Their Application in Drug Delivery” ACS Nano, 2013, 7. 8344.
Impact Factor: 12.062   
7. Fan Xia, Xiaolei Zuo, Alexis Vallée-Bélisle, et al. “High Sensitivity Colorimetric Detection of DNA Sequences, Small Molecules, Proteins and Ions, using Unmodified Gold Nanoparticles and Conjugated Polyelectrolytes” Proc. Natl. Acad. Sci. U. S. A., 2010, 107, 10837.  
Impact Factor: 9.737     
8. Fan Xia, Wei Guo, Youdong Mao, et al. “Gating of single synthetic nanopores by proton-driven DNA molecular motors” J. Am. Chem. Soc., 2008, 130, 8345.    
Impact Factor: 10.677   
Highlight by Nature, Research Highlight, Nature, 453, 19, 960, June 2008  
9. Fan Xia, Xiaolei Zuo, Renqiang Yang, et al. “On the Binding of Cationic, Water-Soluble Conjugated Polymer to DNA: Electrostatic and Hydrophobic Interactions” J. Am. Chem. Soc., 2010, 132, 1252.  
Impact Factor: 10.677   
10. Fan Xia, Xiaolei Zuo, Yi Xiao, et al. “Label-free, Dual-analyte Electrochemical Biosensors: A New Class of Molecular-Electronic Logic Gates”, J. Am. Chem. Soc., 2010, 132, 8557.  
Impact Factor: 10.677   
11. Fan Xia, Ryan White, Xiaolei Zuo, et al. “An electrochemical supersandwich structure assay for sensitive and selective DNA detection in serum” J. Am. Chem. Soc., 2010, 132, 14346.  
Impact Factor: 10.677   
12. Fan Xia, Lin Feng, Shutao Wang, et al. “Dual-responsive Switch Surfaces that switch between Superhydrophilicity and Superhydrophobicity” Adv. Mater., 2006, 18, 432.  
Impact Factor: 14.829  
13. Fan Xia, Hui Ge, Yi Hou, et al. “Multiresponsive surfaces change between Superhydrophilicity and Superhydrophobicity” Adv. Mater., 2007, 19, 2520. 
Impact Factor: 14.829   
It has been featured on Nature China (, a new web-based publication from Nature Publishing Group, the publisher of Nature.  
14. Fan Xia and Lei Jiang “Bio-inspired smart multi-scale interfacial materials” Adv. Mater., 2008, 20, 2842.  
Impact Factor: 14.829     
Most accessed articles in 08/2008: No.1  
Most accessed articles in 09/2007-08/2008 No.2  
Selected as “Special Reprint Issue” Insider Cover
15. Hongwei Xia, Fan Xia,* Yecang Tang, et al. “Tuning Surface Wettability through Supramolecular Interactions ” Soft Matt., 2011, 7, 1638.  
Impact Factor: 3.909   
16. Yongmei Jia, Ruixue Duan, Fan Hong, Boya Wang, Nannan Liu and Fan Xia* “Electrochemical biocomputing: a new class of molecular-electronic logic devices” Soft Matt. 2013, 9, 6571. 
Impact Factor: 3.909   
17. Di Kang, Ryan J. White, Fan Xia,* Xiaolei Zuo,*and Kevin W Plaxco* et al. “DNA biomolecular-electronic encoder and decoder devices constructed by multiplex biosensors” NPG Asia Mater., 2012, 4, 15197.
Impact Factor: 9.042 
18. Fan Xia, Lin Feng and Lei Jiang “Smart responsive surfaces switching between super-hydrophobicity and super-hydrophilicity” Soft Matt., 2009, 5, 275.  
Impact Factor: 3.909 
Top Ten Articles the new top ten most downloaded soft matter articles.  
19. Lin Feng, Yanan Zhang, Jinming Xi, Ying Zhu, Nü Wang, Fan Xia, et al. “Petal Effect: A Superhydrophobic State with High Adhesive Force” Langmuir, 2008, 24, 4114.  
Impact Factor: 4.187
20. Xiaolei Zuo, Fan Xia, et al. “A Sensitive and Selective Amplified Fluorescence DNA Detection Based on Exonuclease III Aided Target Recycling” J. Am. Chem. Soc., 2010, 132, 1816.  
Impact Factor: 10.677
21. Xu Hou, Wei Guo, Fan Xia, et al. “A Biomimetic Potassium Responsive Nanochannel: G-Quadruplex DNA Conformational Switching in a Synthetic Nanopore” J. Am. Chem. Soc., 2009, 131, 7800.  
Impact Factor: 10.677
22. Alexis Vallée-Bélisle, Francesco Ricci, Takanori Uzawa, Fan Xia, et al. “Bioelectrochemical Switches for the Quantitative Detection of Antibodies Directly in Whole Blood” J. Am. Chem. Soc., 2012, 134, 15197.
Impact Factor: 10.677
23. Xiaolei Zuo, Fan Xia, et al. “Two-Step, PCR-Free Telomerase Detection by Using Exonuclease III-Aided Target Recycling” ChemBioChem., 2011, 12, 2745
Impact Factor: 3.740
24. Jingxia Gu, Fan Xia, et al. “Programmable delivery of hydrophilic drug using dually responsive hydrogel cages” J. Control. Release. , 2007, 117, 396.  
Impact Factor: 7.633
25. Liuxuan Cao, Wei Guo, Wen Ma, Lin Wang, Fan Xia, et al. “Towards understanding the nanofluidic reverse electrodialysis system: well matched charge selectivity and ionic composition” Energ. Environ. Sci., 2011, 4, 2259
Impact Factor: 11.653
26. Wenlong Song, Fan Xia, et al. “Controllable Water Permeation on a Poly(N-isopropylacrylamide)-Modified Nanostructured Copper Mesh Film” Langmuir, 2007, 23, 327.  
Impact Factor: 4.187
27. Qiaolan Zhang, Fan Xia, et al. “Wettability switching between high hydrophilicity at low pH and high hydrophobicity at high pH on surface based on pH-responsive polymer” Chem. Commun., 2008, 1199, 1199.  
Impact Factor: 6.378
28. Shutao Wang, Ying Zhu, Fan Xia, et al. “The preparation of a superhydrophilic carbon film from a superhydrophobic lotus leaf” Carbon, 2006, 44, 1845.  
Impact Factor: 5.868
29. Ying Zhu, Lin Feng, Fan Xia, et al. “Chemical dual-responsive wettability of superhydrophobic PANI-PAN coaxial nanofibers” Macromol. Rapid. Comm., 2007, 28, 1135.  
Impact Factor: 4.929
30. Di Kang, Xiaolei Zuo, Renqiang Yang, Fan Xia, et al. “Comparing the Properties of Electrochemical-Based DNA Sensors Employing Different Redox Tags” Anal. Chem., 2009, 81, 9109.  
Impact Factor: 5.695
31. Chenguang Du, Fan Xia, et al. “Advances in Bio-inspired Smart Surfaces with Special Wettability” Chem. J. Chinese. U., 2010, 31, 421.  
Impact Factor: 0.856
32. Wei Guo, Hongwei Xia, Fan Xia, et al. “Current Rectification in Temperature-Responsive Single Nanopores” ChemPhysChem., 2010, 11, 859.  
Impact Factor: 3.349
33. Li Chen, Mingjie Liu, Hao Bai, Peipei Chen, Fan Xia, et al. “Antiplatelet and Thermally Responsive Poly(N-isopropylacrylamide) Surface with Nanoscale Topography” J. Am. Chem. Soc., 2009, 131, 10467.  
Impact Factor: 10.677
34. Yi Guo, Fan Xia, et al. “Switchable Wettability on Cooperative Dual-Responsive Poly-L-lysine Surface” Langmuir, 2010, 26, 1024.  
Impact Factor: 4.187
35. Wei Guo, Hongwei Xia, Liuxuan Cao, Fan Xia, et al. “Integrating Ionic Gate and Rectifier within One Solid-State Nanopore via Modification with Dual-Responsive Copolymer Brushes” Adv. Funct. Mater., 2010, 20, 3561.  
Impact Factor: 9.765
36. Ya-Nan Zhang, Fan Xia, Nu Wang, Lin Feng. “Preparation and characterization of large-area superhydrophobic nanostructured carbon films” Chem. J. Chinese. U., 2007, 28, 568.
Impact Factor: 0.856


Awards and Honors

1. 2013“100 Talent Program”awarded by Hubei government.
2. 2013“Distinguished Professor” awarded by Hubei government.
3. 2012“1000 Young Talent Program”awarded by Chinese government.
4. 2007 “Youth Excellent Academic Performance” awarded by Institute of Chemistry, Chinese Academy of Sciences.  
5. 2007 “First Class of Dean Scholarship” awarded by Institute of Chemistry, Chinese Academy of Sciences.  
6. 2006 “Zhongke Nano Fellowship” awarded by Institute of Chemistry, Chinese Academy of Sciences.  
7. 2006 “Youth Excellent Academic Performance” awarded by Institute of Chemistry, Chinese Academy of Sciences.  
8. 2006 “First Class of Dean Scholarship” awarded by Institute of Chemistry, Chinese Academy of Sciences.  
9. 2004 “Special Prize of the President Scholarship” awarded by Chinese Academy of Sciences.
10. 2003 “First Class Scholarship” awrded by Chinese Government Scholarship.  
11. 2002 “Excellent Student” awarded by Huazhong University of Science and Technology. (one of 20 students in about 20,000 students)  
12. 1999 ~ 2002 “First Class Scholarship” awarded by Huazhong University of Science and Technology for four times for three times.  


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