Associate Professor of Chemistry

Phone: (86)27-87543032


Academic Areas: polymer chemistry

Dr. Shen Lei received his B.S. in chemistry at the University of Science and Technology of China (USTC) in 2003. In 2008, he obtained his Ph.D. in chemistry as an united student under the supervision between Prof. Chi Wu at USTC and Prof. Mitchell A Winnik at University of Toronto. It was there that he received a rigorous training in polymer physics. From 2009 to 2012, he moved to University of Minnesota as the postdoctoral fellow in Prof. Timothy P Lodge and Prof. Xiaoyang Zhu’s research groups, working on protein interaction with bio-interfaces. In Dec 2012, he went to Columbia University as an associate research scientist. He joined Huazhong University of Science and Technology in Nov 2013 as an associate professor. His research currently focuses on the physics and chemistry of bio-interfaces through combination of polymer chemistry, colloid science and chemical biology.

Academic Degrees

PhD in polymer chemistry, 2008, University of Science and Technology of China & University of Toronto;

BA in chemistry, 2003, University of Science and Technology of China.

Professional Experience

University of Minnesota, Postdoc Researcher (2009-2012);

Columbia University, Associate Research Scientist (2012-2013);

Huazhong University of Science and Technology, Associate Professor (2013-present)

Selected Publications

1. Lei Shen, Yini Wang, Chia-I Lin, Hung-wen Liu, Athena Guo, X.-Y. Zhu. Membrane Enviroment Can Enhance the Interaction of Glycan Binding Protein to Cell Surface Glycan Receptors. ACS Chem. Biol. 2014, accepted.
2. Lei Shen, Takuji Adachi, David Vanden Bout, X.-Y. Zhu. A Mobile Precursor Determines Amyloid-β Peptide Fibril Formation at the Liquid-Solid Interface. J. Am. Chem. Soc. 2012, 134, 14172-14178.
3. Lei Shen, Adam Garland, Yini Wang, Zicheng Li, Christopher W. Bielawski, Athena Guo, X.-Y. Zhu. Two Dimensional Nanoarrays of Individual Protein Molecules. Small 2012, 8, 3169-3174.
4. Lei Shen. (Invited Review) Biocompatible Polymer/Quantum Dots Hybrid Materials: Current Status and Future Developments. J. Funct. Biomater. 2011, 2, 355.
5. Lei Shen, X.-Y. Zhu. Evidence of a mobile precursor state in non-specific protein adsorption. Langmuir, 2011, 27, 7059.
6. Lei Shen, Athena Guo, X.-Y. Zhu. Tween Surfactants: Adsorption, Self-Organization, and Protein Resistance. Surface Sci. 2011, 605, 494.
7. Lei Shen, Hai Wang, Gerald Guerin, Chi Wu, Ian Manners, Mitchell A. Winnik. A Micellar Sphere-to-Cylinder Transition of Poly(ferrocenyl-
dimethyl-silane-b-2-vinylpyridine) in a Selective Solvent Driven by Crystallization. Macromolecules, 2008, 41, 4380.
8. Lei Shen, Andrij Pich, Daniele Fava, Mingfeng Wang, Sandeep Kumar, Chi Wu, Gregory D. Scholes, Mitchell A. Winnik. Loading Quantum Dots into Thermo-responsive Microgels by Reversible Transfer from Organic Solvents to Water. J. Mater. Chem., 2008, 18, 763.
9. Lei Shen, Ronald Soong, Mingfeng Wang, Anna Lee, Chi Wu, Gregory D. Scholes, Peter M. Macdonald, Mitchell A. Winnik. Pulsed Field Gradient NMR Studies of Polymer Adsorption on Colloidal CdSe Quantum Dots. J. Phys. Chem. B, 2008, 112, 1626.
10. Lei Shen, Jianzhong Du, Steven P. Armes, Shiyong Liu. Kinetics of pH-Induced Formation and Dissociation of Polymeric Vesicles Assembled from a Water-Soluble Zwitterionic Diblock Copolymer. Langmuir. 2008, 24, 10019.
11. Lei Shen, Guangzhao Zhang. The Formation of Mesoglobules by Poly(N,N-diethylacrylamide) Homopolymer Chains in Dilute Solutions. Chinese Journal of Polymer Science. 2009, 27, 561.

Courses Taught

Special Polymer Materials; Material Chemistry; Chemical simulation training