1. General information
Course code：CHE0031
Course name： Organic Chemistry
Class hours/Credits：96/6
lecturing hours：52 ； laboratory hours：44 ； Off- class hours： 42
Major of targeted students： Clinical MBBS
Department providing course ： School of chemistry and chemical engineering
2. Course description and goals
Organic chemistry is a subject that studies the properties, synthesis and reactions of organic compounds. It is one of the important basic courses in chemistry, biochemistry and the medical subjects. This course is carried out as followed:
1. To emphasize the "three foundations" (basic theory, basic knowledge, basic operation skills) to actively cultivate students' self-learning ability, innovation ability, observation ability, analysis and problem solving ability, developing a good style of study for seeking truth from facts.
2. To help students acquire the necessary basic knowledge of organic chemistry to understand the development frontier of organic chemistry, fully understand the important role of organic chemistry in various disciplines of chemistry, life, materials, energy, environment and other disciplines, and master the general methods to explore the basic laws of organic chemistry. Guide students to accept the knowledge of organic chemistry, improve the basic quality of organic chemistry.
3. Students are required to be proficient in reading and understanding organic chemistry English textbooks and literature.
4. To guide the students to analyze the function of biomolecules in biology with the knowledge of organic molecules, and to lay a solid foundation for the further study of medical subjects.
3. Basic contents and requirements
(1) Attitude
Students of the program are required the standardized operation habits with rigorous and realistic scientific styles of work.
(2) Basic theory and knowledge
General laws and theories of organic chemistry: atomic orbital theory, molecular orbital theory, valence bond theory, acid-base theory, stereochemistry, structure-property relationships
Nomenclature and isomerism of organic compounds; The main physical properties of organic compounds and their variation laws; The chemical properties and preparation of various organic compounds；The mechanism of organic chemical reactions (free radical substitution, electrophilic substitution, nucleophilic substitution, electrophilic addition, nucleophilic addition, etc.); Electronic effect and steric effect of organic molecular structure; Mechanism analysis of organic reaction；Analysis of stereochemistry; Synthetic design of organic compounds；Structural characteristics and important reactions of several kinds of biological molecules.
(3) Basic skills
Be familiar with laboratory safety rules, master common accident treatment methods, washing and drying of common instruments, recrystallization operation, simple distillation device, principle and operation of chromatography method, principle and operation of electrophoresis, principle and operation of extraction device, simple organic matter synthesis method.
4. Course schedule and hours allotment
Contents |
Lecturing hours |
Laboratory hours |
Off-class hours |
Introduction & Preface |
6 |
|
3 |
Alkanes and cycloalkanes |
6 |
|
3 |
Alkenes and Alkynes |
6 |
|
3 |
Aromatic compounds |
4 |
|
2 |
Stereochemistry |
4 |
|
2 |
Halohydrocarbons |
2 |
|
2 |
Alcohols, phenols, ethers |
4 |
|
2 |
Aldehydes and ketones |
6 |
|
3 |
Carboxylic Acids and Substitutional acids |
4 |
|
2 |
Amines & Proteins |
4 |
|
2 |
Carbohydrates & Nucleic acids |
4 |
|
2 |
Introduction to Organic Experiments |
|
4 |
2 |
Ordinary Distillation |
|
4 |
2 |
Recrystallization |
|
6 |
2 |
Thin-layer Chromatography |
|
6 |
2 |
Extraction of Caffeine from Tea Leaves |
|
6 |
2 |
N-butyl Bromide |
|
6 |
2 |
Isoamyl Acetate |
|
6 |
2 |
Aspirin |
|
6 |
2 |
Total |
52 |
44 |
42 |
5. Text book
(1) Organic Chemistry ---for Students of Medicine and Biology (第二版). 夏淑贞，罗一鸣，冯文芳. 华中科技大学出版社，2012年；
(2) 基础有机化学实验（下），周井炎，华中科技出版社；
For extracurricular materials:
(1)有机化学. 李艳梅，赵印圣，王兰英等，科学出版社，2010.
(2)基础有机化学（第四版）. 邢其毅，裴伟伟，徐瑞秋，裴坚等, 北京大学出版社
(3)Organic chemistry (Ninth edition). John McMurry. Cengage Learning , 2015 （ISBN：978-1-305-08048-5）
(4)Experimental Organic Chemistry——for Students of Medicine and Biology（中英文对照），冯文芳，陈东红，叶晓霞等。华中科技大学出版社，2013
(5)有机化学实验技术，科学出版社出版，有机化学实验技术编写组编
6. Evaluation/Grading policy
This course evaluation consists of four parts：
1.Final exam：40% (Close-book test)
2.Overall rating on lab work：30%
3.Evaluation of self-learning and homework：20%
4.Classroom performance：10%
Drafter： Feng Wenfang
