Using chemical means to explore the relationship between life sciences and molecular chemistry, and thus guide the synthesis of new drugs and the development of new bio analytical techniques and medical diagnostic techniques, including biochemistry, biocatalytic synthesis chemistry, structural protein biology and drug research, nano biochemistry and several other directions.
1) Biochemistry and Application:
Focusing on the structure and function of selenoproteins and human health; the mechanisms of protein tyrosine nitration and oxidation catalyzed by iron and iron porphyrin and their relationship with the development of major diseases; the cellular biological effects caused by the interaction of small molecules, such as insulin signaling, cell differentiation, and so on.
2) Biocatalytic Synthesis of Chemical:
Focusing on biocatalytic organic synthesis reaction, biomimetic catalytic reaction, enzyme and cell immobilization technology, pharmaceutical intermediates synthesis, the development of fluoride bioactive substances, and so on.
3) Nano biochemistry and Drug Research and Development:
Focusing on the structure of protein in the non-folded state; the research of the interaction interface of protein complexes; the regulation of peptide aggregation and depolymerization; the research and development of antibacterial peptide and dendritic peptide drug; the development of the organic small molecule drug; the establishment of the nano-drug loaded system and bio-analytical system based on biological macromolecule template; the construction of the intelligent nano-sustained release gel.